|
Symbol Name ID |
Myc
myelocytomatosis oncogene MGI:97250 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Abnormality of the pancreas |
| Disease(s) Associated with MYC | |
| Burkitt lymphoma |
| Mouse Phenotypes | abnormal pancreatic acinus morphology |
abnormal pancreatic acinar cell morphology |
absent pancreatic acinar cells |
abnormal pancreatic duct morphology |
exocrine pancreas atrophy |
abnormal large intestine crypts of Lieberkuhn morphology |
abnormal small intestine crypts of Lieberkuhn morphology |
decreased Paneth cell number |
endocrine/exocrine gland phenotype |
pancreatic islet hyperplasia |
enlarged thymus |
abnormal mammary gland morphology |
abnormal mammary gland development |
abnormal branching of the mammary ductal tree |
abnormal involution of the mammary gland |
mammary gland duct hyperplasia |
abnormal mammary gland lobule morphology |
abnormal mammary gland alveolus morphology |
mammary gland alveolar hyperplasia |
increased mammary gland tumor incidence |
increased mammary adenocarcinoma incidence |
mammary gland hyperplasia |
abnormal pancreas development |
abnormal pancreas morphology |
abnormal pancreas size |
decreased pancreas weight |
small pancreas |
pancreas hypoplasia |
seminiferous tubule degeneration |
increased Leydig cell number |
decreased testis weight |
increased pancreas tumor incidence |
increased pancreatic acinar cell carcinoma incidence |
increased pituitary gland tumor incidence |
increased T cell derived lymphoma incidence |
lactation failure |
abnormal mammary gland epithelium physiology |
increased mammary gland apoptosis |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||||||||||||||||
| Bmyctm1Mpo/Bmyctm1Mpo | |||||||||||||||||||||||||||||||||||||||
| Myctm1.1Itl/Myctm1.1Itl | |||||||||||||||||||||||||||||||||||||||
| Tg(Ela1-Myc)158Bri/0 | |||||||||||||||||||||||||||||||||||||||
| Tg(Ela1-Myc)159Bri/0 | |||||||||||||||||||||||||||||||||||||||
| Tg(Ela1-Myc)160Bri/0 | |||||||||||||||||||||||||||||||||||||||
| Tg(IghMyc)22Bri/0 | |||||||||||||||||||||||||||||||||||||||
| Tg(MMTV-Myc)141-3Led/0 | |||||||||||||||||||||||||||||||||||||||
| Tg(MMTV-Myc)WT13Jrn/0 | |||||||||||||||||||||||||||||||||||||||
| Tg(MMTV-Myc)WT21Jrn/0 | |||||||||||||||||||||||||||||||||||||||
| Tg(MMTV-Myc*T58A)TA14Jrn/0 | |||||||||||||||||||||||||||||||||||||||
| Tg(MMTV-Myc*T58A)TA39Jrn/0 | |||||||||||||||||||||||||||||||||||||||
| Tg(MMTV-Myc*T58A)TA41Jrn/0 | |||||||||||||||||||||||||||||||||||||||
| Tg(Pklr-Myc)73Ak/0 | |||||||||||||||||||||||||||||||||||||||
| Tg(Thy1-cmyc)6Kio/0 | |||||||||||||||||||||||||||||||||||||||
| Tg(Thy1-cmyc)6LKio/0 | |||||||||||||||||||||||||||||||||||||||
| Tg(WapMyc)212Bri/0 | |||||||||||||||||||||||||||||||||||||||
| Gt(ROSA)26Sortm1(Myc)Rcse/Gt(ROSA)26Sortm1(Myc)Rcse Tg(Wap-cre)11738Mam/0 (conditional) |
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| Gt(ROSA)26Sortm2(myc*T58A)Rcse/Gt(ROSA)26Sortm2(myc*T58A)Rcse Tg(Wap-cre)11738Mam/0 (conditional) |
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| Gt(ROSA)26Sortm3(myc*S62A)Rcse/Gt(ROSA)26Sortm3(myc*S62A)Rcse Tg(Wap-cre)11738Mam/0 (conditional) |
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| Myctm2.1Atp/Myctm2.1Atp Tg(Pdx1-cre)1Herr/0 (conditional) |
* | ||||||||||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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